ABSTRACT
It is described a case of a 30-year-old health worker who presents a clinical state compatible with reinfection by SARS-CoV-2 or with a false positive diagnostic test for active infection. The temporal sequence of tests performed and symptoms presented are described. The first cases of SARS-CoV-2 disease were reported in December 2019 and to date, knowledge of the diagnostic tests is under continuous review.
ABSTRACT
Objectives: The COVID-19 disease is a public health emergency of international importance and vaccination is considered the best tool against it. The objective of this study was to evaluate the possible adverse reactions to the vaccine against COVID-19 reported by workers at a tertiary hospital in Madrid. Making a description of the frequency, the presence in the technical sheet, the association with the history of infection by SARS-COV-2 and age. Methods: A retrospective descriptive study of the possible adverse reactions reported to the Occupational Risk Prevention Service of the hospital after the administration of the two doses of the vaccine for COVID-19 (Comirnaty®) was carried out in a sample of 8446 workers that received the first dose 1 and 8255 that received the second. A comparative analysis was performed by applying Pearson’s Chi-square test for qualitative variables and the Mann-Whitney test for quantitative variables. Results: The subjects who reported adverse reactions were 207 after dose 1 (2.45% of total vaccinated) and 397 after dose 2 (4.80% of total vaccinated). 76.8% were older than 55 years (dose 1) and 15.9% with dose 2. 57% had symptoms that were already described in the technical data sheet (dose 1) and 70.5% with dose 2. 50.7% had been previously diagnosed with COVID-19 (dose 1) and 30.5% with dose 2. Conclusions: The adverse reactions reported in our study have been mild or moderate, coinciding with the studies consulted. Adverse reactions were more frequent after the second dose. Among the workers who reported adverse reactions, there were more with a history of COVID-19, especially after the first dose. The reactions produced after vaccination and their causal relationship with it should continue to be studied. © 2021, Accion Medica S.A.. All rights reserved.